Hemicholinium dibromide ( HC3 | HC 3 | HC-3 | Hemicholinium3 | Hemicholinium 3 )

产品货号. M13999 CAS No. 312-45-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Hemicholinium dibromide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

胆碱高亲和力摄取系统的有效抑制剂。它对低亲和力摄取系统影响较小。
产品描述

A potent inhibitor of the high affinity uptake system for choline. It has less effect on the low affinity uptake system. Since choline is one of the components of acetylcholine, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
体外实验

Cell Viability Assay Cell Line:The human small cell lung carcinoma cell line NCI-H69 Concentration:1 mM Incubation Time:Added every day for 2 days. Result:Markedly inhibited cell viability.
体内实验

——
同义词

HC3 | HC 3 | HC-3 | Hemicholinium3 | Hemicholinium 3
通路

Others
靶点

Other Targets
受体

ChR
研究领域

——
适应症

——

CAS Number

312-45-8
分子量

574.35
分子式

C24H34Br2N2O4
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM
SMILES

OC1(C2=CC=C(C3=CC=C(C4(O)OCC[N+](C)(C)C4)C=C3)C=C2)OCC[N+](C)(C)C1.[Br-].[Br-]
化学全称

2,2'-([1,1'-biphenyl]-4,4'-diyl)bis(2-hydroxy-4,4-dimethylmorpholin-4-ium) bromide

1.Soukup O, et al. Toxicol Lett. 2012 Aug 3;212(3):315-9.

计算器

产品手册

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